Astros vs. Guardians Prediction, Odds, Picks – July 7

Astros vs www.771. Guardians Prediction, Odds, Picks – July 7

Updated: July 7, 2025, 8:00 p.m. ET

The Houston Astros, led by Jose Altuve, are set to kick off a three-game series against Steven Kwan and the Cleveland Guardians on Monday at Daikin Park. The Guardians come into this matchup as +110 moneyline underdogs against the favored Astros (-131). Houston is also favored on the run line at -1.5, while a 7.5-run over/under has been established.

Here’s everything you need to know from a betting perspective about the Astros-Guardians game, including run line, moneyline, totals, and expert picks. Keep up with MLB action on FOX Sports.

Astros vs. Guardians Game Information & Odds

When: Monday, July 7, 2025, at 8:10 p.m. ET

Where: Daikin Park in Houston, Texas

How to Watch on TV: SCHN and CLEG

Favorite	Favorite Moneyline	Underdog Moneyline	Total Over	Total Odds	Under Total Odds	Run Line Favorite	Run Line Odds	Underdog Run Line Odds
Astros	-131	+110	7.5	+102	-124	-1.5	+156	-190

Astros vs. Guardians Prediction

Score Prediction: Astros 5, Guardians 4

Total Prediction: Over 7.5 runs

Win Probabilities: Astros 58%, Guardians 42%

Astros vs. Guardians Betting Insights

The Astros have been favoured in 62 games this season, winning 38 of those (61.3%). In 37 games this year where they were favoured by -131 or more, they boast a 26-11 record. The books suggest a 56.7% chance of victory for Houston.

The Guardians have faced off as underdogs 55 times this season, claiming victory 21 times (38.2%). Cleveland has secured nine wins in 32 matches as underdogs with a moneyline of at least +110 or worse, implying a 47.6% chance of winning according to the odds set by the bookmakers.

Astros Recent Betting Performance

The Astros went 5-2 in their last 10 matchups where they were moneyline favorites live dealer games. In those 10 games, both the Astros and their opponents combined to surpass the set run total five times. The Astros also have a record of 6-4-0 against the spread in their recent games.

Astros Recent Stats

Stat	Avg/Total
Record	8-2
Runs Per Game	6.0
Home Runs	16
ERA	3.84
K/9	8.8

Astros Player Insights

Isaac Paredes currently leads the team with 18 home runs and 48 RBIs. Among all hitters in baseball, he ranks 20th in home runs and 49th in RBIs. Paredes is on a five-game hitting streak, batting .333 in that span.

Jose Altuve has a batting average of .272 with 12 doubles, a triple, 16 home runs, and 31 walks. ph365 .com He ranks 33rd in home runs and 57th in RBIs among all major league batters. Altuve is also on a quest for his sixth consecutive game with a hit, batting .500 in his last five outings.

Jake Meyers is batting .308 and has also made a significant impact with 15 doubles, two triples, and three home runs. He has shown a consistent performance lately.

Astros Team Props

Player	Hits O/U	Total Bases O/U	HR O/U	RBI O/U
Jose Altuve	0.5 (-240)	1.5 (+140)	–	0.5 (+185)
Isaac Paredes	0.5 (-200)	1.5 (+135)	–	0.5 (+210)

Guardians Recent Betting Performance

The Guardians have played as underdogs eight times in their last 10 games without a win in any of those encounters. In their last 10 games with a total, they and their opponents have gone over the set total three times. Cleveland has managed to cover the spread four times in that same span. pvl.ph live stream

Guardians Recent Stats

Stat	Avg/Total
Record	0-10
Runs Per Game	1.5
Home Runs	6
ERA	4.44
K/9	8.5

Guardians Player Insights

Jose Ramirez leads the Guardians with 14 home runs and 39 RBIs, ranking 45th in homers and 88th in RBIs across MLB. Steven Kwan is hitting 8k89 vip.298 to lead those in the lineup, while Carlos Santana has put himself on the board with seven doubles and 10 home runs this season.

Guardians Team Props

Player	Hits O/U	Total Bases O/U	HR O/U	RBI O/U
Steven Kwan	0.5 (-270)	1.5 (+130)	–	0.5 (+295)
José Ramírez	1.5 (+180)	1.5 (-110)	–	0.5 (+155)

What do you think will happen in the upcoming game between the Astros and Guardians?